The Center for Clinical Epidemiology and Biostatistics (CCEB), the Department of Biostatistics and Epidemiology (DBE), and the Graduate Group in Epidemiology and Biostatistics occupy approximately 34,000 net square feet in 140 offices plus 20 workstation/computing pods located on seven floors in Blockley Hall. Within this space, the CCEB, DBE, and Graduate Group maintain a seminar/lecture room with a capacity for 60 people; three large, 16-person conference rooms; and a computing resource center.
Blockley Hall is adjacent to the main medical school buildings and a short distance from the Hospital of the University of Pennsylvania, Children's Hospital of Philadelphia, the Clinical Research Building, the John Morgan Building, and the University's main campus. The Department of Statistics at the Wharton School, located on the main campus, is a short walk from Blockley Hall.
The CCEB also occupies approximately 1,200 net square feet of laboratory space in BRB II/III, a research building located across the street from Blockley Hall. Finally, the CCEB has additional offices within the University City Science Center complex located on the Market Street corridor known as the "Avenue of Technology," at the northern edge of the Penn campus. The CCEB occupies approximately 3,200 square feet of space at 3401 Market, including a large conference room and offices for approximately 15 staff. An additional 8,700 square feet is provided at 3535 Market, with office space for approximately 50 staff. This space includes two conference rooms and a machine room configured with controlled HVAC and uninterrupted electric power supplies providing controlled air and power.
Timothy Rebbeck, Ph.D., Professor of Epidemiology and CCEB faculty member, directs the Laboratory for Molecular Epidemiology (LME) at the University of Pennsylvania. A primary LME goal is to conduct molecular epidemiology laboratory studies that are unavailable in the School of Medicine's genotyping core facility. The laboratory itself occupies approximately 1200 net square feet in the BRB II/III building, adjacent to the CCEB offices in Blockley Hall. The LME is a state-of-the-art facility dedicated to DNA polymorphism typing for epidemiological and family-based studies. In close proximity to basic science and clinical research colleagues and staff associated with the CCEB, the LME is ideally located for conducting multidisciplinary studies.
The CCEB manages a state-of-the-art research computing facility to support biostatistical, epidemiologic, basic, clinical and translational health research. The CCEB's computing environment is managed by the Clinical Research Computing Unit (CRCU), a designated "Core Research Facility" situated within the CCEB. The CRCU offers two distinct types of services: research computing as well as data and project management for clinical trials, epidemiologic studies, and cooperative basic-science studies; and research computing and information technology support to faculty, fellows, trainees, and staff within the CCEB.
The CCEB operates a network of 14 Unix servers supporting user and database services for the various entities and research projects within the CCEB. There are also nine Win2K/Win-NT servers that provide additional user profiles, file, and print services. These servers have a diverse set of functions, including e-mail; calendar; network, project, user files, and directory services; printing support; and security. The servers are configured with at least 1 gigabyte (GB) of primary memory and dual Ethernet connections, running at a full 100Mb/sec bandwidth per connection.
Users of CCEB computing services (faculty, trainees, and staff of the CCEB) have access to central computing resources through uniformly configured Windows 2000 workstations in their offices. In addition to general utility services such as mail, calendars and Internet access, the CCEB computing system offers a range of specialized programs such as Oracle (for database applications); SAS, S-Plus, STATA, StatXact, SUDAAN, Gauss, MatLAB, Mathematica, and Egret (for statistical analysis); programming languages such as Fortran, C, C++, Java, and Perl; and various other graphics, text processing, and general productivity tools.
In addition to the CCEB's own resources, its faculty draw on the outstanding educational and research resources of the University of Pennsylvania. Penn is home to a diverse body of 10,000 students enrolled in its 12 graduate and professional schools, each a national leader in its field. Penn's schools are located on a compact campus the geographical unity of which supports and fosters its multidisciplinary approach to education, scholarship, and research. Penn's research and research training are substantial and esteemed enterprises, with a research community including more than 1,000 faculty, 1,000 postdoctoral fellows, 3,000 Ph.D. students, and 5,000 professional, administrative, and support staff bolstered by an annual budget exceeding half a billion dollars. Penn's university-wide 25 centers and institutes bring together researchers from multiple departments, schools, and disciplines.
CCEB faculty also benefit from the School of Medicine and its innovative record in clinical and basic science, which features numerous landmark achievements. The School of Medicine is supported by state-of-the-art research core facilities and major clinical research facilities. The School has an internationally renowned research faculty and programs in all fundamental areas of basic and clinical biomedical science. New construction of 771,000 gross sq. ft. and the renovation of 658,000 gross sq. ft. of education and research space from FY 1989 through FY 2001 resulted in the doubling of research space. Plans are also underway to build a new research and training facility scheduled to open in 2006. Further, the School of Medicine and Children's Hospital of Philadelphia have jointly identified 16.7 acres of property adjacent to the medical center complex for future development.